Skip to main content

Posts

Showing posts from January, 2023

GPCR signaling and its importance as a pharmacological target

  Introduction There are several important concepts in biochemistry that explain how certain things work in our bodies. Of these, cellular communication is a crucial topic to discuss. Through the elegance of this complex process, our body is able to establish communication routes to produce a desired outcome. Have you ever wondered how you know you are hungry? Or how do your hands quickly move away if you accidentally touch something extremely hot? Your body has its own USPS system that serves to establish communication channels to respond to various environmental stimuli.  One such important cellular communication platform is the GPCR signaling or the G-protein coupled receptors. These receptors are highly expressed in the human genome and are responsible for signal transduction in various metabolic pathways. 1 Hence, serving as a major pharmacological target to treat numerous metabolic diseases.  In this blog, I am going to discuss the basics of GPCRs mediated signal transduct